Since 1998 our group has been fighting the use of herbicides to control guardrail weeds by Massachusetts Highway and Massachusetts Turnpike Authority, state agencies recently combined as The Massachusetts Department of Transportation. The basis for our opposition is the proven toxicity of the chemicals which enter streams beneath guardrails along the state's 4,000+ miles of roads, then flow into rivers and wetlands and finally find their way to drinking-water aquifers. As a result the toxins have been found not only in frogs and other species of wildlife, but in the growing bodies of children who live along those roads. Our organization, based in western Mass, partnered in early 1999 with Toxics Action Center of Boston to form a campaign that successfully stopped the practice statewide for 5 years. The spray-program was resumed in 2005 under the succeeding administration but only for the state's eastern roadways and along its high-speed limited-access highways; for the past two years solely the latter, mostly Interstates, due to the state's budget shortfall. We expect to ramp-up active, community-based opposition in an improving economy if the state attempts to upscale the program.